Our Solution 

SensPD has developed a revolutionary and patent-pending system to objectively detect autism at a very early developmental stage, based on a physiological marker. We use Oto-Acoustic-Emission (OAE) devices, used in every hospital in the western world to screen for hearing issues. We take them to the next level with IP protected changes to measure the sensory perception system performance and thus detect autism.

 

Our solution is: objective, model based, non-invasive (it is like a hearing test), we believe can be measured after birth, easy and simple it only take a few minutes and cost effective.

The Need

How early in life can you detect autism?

Current diagnosis procedure is subjective, based on the observation of behaviors (listed in DSM5) manifested only around the age of 2 years. The current process is long and expensive and it dramatically limits and delays early intervention treatments. This is exactly where SensPD come into place.

Early Interventions:

It is known interventions applied as soon as possible (6-12 months), result in better than 90% success rate in ingraining skills allowing for social integration. It means that more kids with ASD would be able to attend the general education system, be able to play and communicate better with their peers and become a productive member of society. SensPD’s devise and method for early objective detection of autism has the potential to change the lives of millions around the world.

Autism Prevalence:

According to the latest CDC report, autism prevalence today is 1:59 in the US.. According to the Ministry of Health in Israel the prevalence is 1:100.

The European Union (ASDEU) reports the prevalence as between 1% and 2%.

The Burden of Autism:

The burden of autism is very high, and it has a ripple effect - it affects individuals with ASD, the families, the community the local and national Health and Education systems.

According to the CDC, the annual medical costs per person with autism are about $11,000, behavioral treatments cost between $40,000 and $60,000. Lifetime expenses may reach 2.9 million dollars.

Reports forecast that the annual cost related to autism in the U.S. by the year 2025 will be 461 billion dollars.

The Science & Technology

Focusing on hearing, the most social of the senses and specifically
on the intriguing phenomenon of Oto-Acoustic Emissions (OAE), a
model was built that puts the outer hair cells (which generate OAE)
response, as the centerpiece of sensory processing.

 

A review of stochastic signals generated in the neural system and their
effect on sensory information processing have shown that stochastic
neural activity initiated by the outer hair cells (OAE) influences
computations in other brain sites.  The neural activity associated
with audible sound frequencies implies that the influence of cells
located in the inner ear is widespread. 

 

Thus, it was demonstrated that the same auditory noise can enhance the sensitivity of tactile, visual, and proprioceptive system responses to weak signals.  Specifically, the effective auditory noise significantly increases tactile sensations of the finger, decreased luminance and contrast visual thresholds and significantly changed EMG recordings of the leg muscles during posture maintenance.
 

Frith and Baron-Cohen hypothesized that the main abnormality in autism is a deficiency in the ability to construct a “theory of other minds (TOM)”.  They argue that specialized neural circuitry in the brain allows formulation of sophisticated hypotheses about the inner workings of other people’s minds.  These hypotheses, in turn, enable useful predictions about others’ behavior.  TOM and other explanations imply that the sensory system provides reliable information that is than mis-interpreted.  In SensPD we believe that the failure of SP is behind TOM and other similar theories.
 

SensPD’s inventive step is the association of OAE measurement with SP and its performance, that is why SensPD’s approach allows for a very early objective diagnosis of autism.

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